✦ LIBER ✦

Studies on the reactivity of acyl glucuronides—II: Interaction of diflunisal acyl glucuronide and its isomers with human serum albumin in vitro

✍ Scribed by Ronald G. Dickinson; Andrew R. King

Book ID: 115782141
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 776 KB
Volume: 42
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(91)90233-u

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

In vitro assessment of the interactions

In vitro assessment of the interactions between diclofenac and tolmetin acyl glucuronide drug metabolites and human serum albumin

✍ Thomas G. Hammond; Sophie L. Regan; Xiaoli Meng; James L. Maggs; Rosalind E. Jen 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 97 KB

Interaction of human serum albumin with

Interaction of human serum albumin with furosemide glucuronide: a role of albumin in isomerization, hydrolysis, reversible binding and irreversible binding of a 1-O-acyl glucuronide metabolite

✍ Takashi Mizuma; Leslie Z. Benet; Emil T. Lin 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB 👁 2 views

Furosemide 1-O-acyl glucuronide (Fgnd) was reversibly bound to a single class of binding sites on human serum albumin (HSA), and the binding of Fgnd decreased with increasing F concentrations, suggesting that Fgnd binds to the same warfarin binding sites on HSA as F binds. The rate of Fgnd degradati

Studies on the reactivity of acyl glucur

Studies on the reactivity of acyl glucuronides—V. Glucuronide-derived covalent binding of diflunisal to bladder tissue of rats and its modulation by urinary pH and β-glucuronidase

✍ Ronald G. Dickinson; Andrew R. King 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 932 KB

NMR Spectroscopic Studies on the in Vitr

NMR Spectroscopic Studies on the in Vitro Acyl Glucuronide Migration Kinetics of Ibuprofen ((±)-( R , S )-2-(4-Isobutylphenyl) Propanoic Acid), Its Metabolites, and Analogues

✍ Johnson, Caroline H.; Wilson, Ian D.; Harding, John R.; Stachulski, Andrew V.; I 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 133 KB