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Studies on the imidazo[4,5-d]pyridazine ring system. Course of alkylation of imidazo[4,5-d]pyridazine-4-thione

โœ Scribed by Chen, Shih-Fong; Panzica, Raymond P.


Book ID
118012978
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
983 KB
Volume
46
Category
Article
ISSN
0022-3263

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Two synthetic routes to the versatile 3,5-dihydro-imidazo [4,5-d]pyridazin-4-ones 2 and 5 have been developed that allow the production of multigram quantities without the need of any chromatographic purification. Broad and selective elaboration of the heteroaromatic scaffolds has also been accompli