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Studies on the alkylation of chiral enolates: application toward the total synthesis of discodermolide

โœ Scribed by Clark, David L.; Heathcock, Clayton H.


Book ID
127231535
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
178 KB
Volume
58
Category
Article
ISSN
0022-3263

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A strategy of tandem ketene-trapping/IMDA toward the total synthesis of the hirsutellones was attempted. The AB ring moiety of the hirsutellones was constructed with the proper stereochemistry.