Studies on pyrazines. 35. An improved synthesis of bromopyrazines from hydroxypyrazines

✍ Scribed by Nobuhiro Sato; Nobuhiko Narita

• Book ID: 102341344
• Publisher: Journal of Heterocyclic Chemistry
• Year: 1999
• Tongue: English
• Weight: 271 KB
• Volume: 36
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570360334

✦ Synopsis

Abstract

The synthesis of bromopyrazines from hydroxypyrazines was successfully effected by the procedure via trimethylsilyloxypyrazines, the sequence of which proceeds under mild conditions and does not require the isolation of intermediate.