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Studies on Production of Anticollagen Antibodies in Silicosis

✍ Scribed by T. Nagaoka; M. Tabata; K. Kobayashi; A. Okada


Book ID
115600493
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
953 KB
Volume
60
Category
Article
ISSN
0013-9351

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Circulating antibodies to native and denatured types I and I1 human and bovine collagens were assayed in patients with rheumatoid arthritis (RA), patients with other rheumatic diseases, and normal individuals. A subgroup of this population was also assayed for reactivity with typing reagents which d

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## Abstract ## Objective Type II collagen (CII)–specific B cell responses have been recognized in human rheumatoid arthritis (RA) and in collagen‐induced arthritis (CIA). An important limitation of the CIA model is that the CII response and the disease are stimulated by exogenously injected collag