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Studies on preventive effects of diphenyl diselenide on acetaminophen-induced hepatotoxicity in rats

✍ Scribed by Ethel A. Wilhelm; Cristiano R. Jesse; Marlon R. Leite; Cristina W. Nogueira

Book ID
119343421
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
673 KB
Volume
16
Category
Article
ISSN
0928-4680

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Cimetidine has been shown to protect against acetaminophen-mediated hepatotoxicity in both rats and mice. In contrast to cimetidine, ranitidine recently has been determined to potentiate the hepatotoxic action of acetaminophen in Fischer 344 rats. The present studies were designed to characterize th