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Studies on metabolism and identification of the causative agent in aspirin teratogenesis in rats

โœ Scribed by Kimmel, Carole A. ;Wilson, James G. ;Schumacher, Herbert J.

Book ID
112216181
Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
800 KB
Volume
4
Category
Article
ISSN
0040-3709

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Aspirin-induced teratogenesis: A unique
Aspirin-induced teratogenesis: A unique pattern of cell death and subsequent polydactyly in the rat
โœ Klein, Kenneth L. ;Scott, William J. ;Wilson, James G. ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 569 KB

## Abstract Offspring of pregnant rats treated with a high dose of aspirin on day 11 of gestation frequently had predominantly rightโ€sided polydactyly of the hindlimbs at term. Aspirinโ€treated embryos removed on day 12 exhibited a unique pattern of preaxial mesodermal cell death in the hindlimb bud