Studies on mechanism of action of glycyrrhizin against hepatitis a virus replication in vitro
✍ Scribed by Jean-Marc Crance; Françoise Lévêque; Evangélos Biziagos; Hélène van Cuyck-Gandré; Alain Jouan; Robert Deloince
- Book ID
- 118393364
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 714 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0166-3542
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The effect of protamine, atropine, selenocystamine, taxifolin, and catechin on the infectivity and antigenicity of the cell culture-adapted hepatitis A virus (HAV) strain CF 53 was studied. The toxicity on uninfected PLC/PRF/5 cells was examined for each antiviral compound by morphological and bioch
## Abstract Forty antiviral compounds were screened for inhibitory effect on hepatitis A virus (HAV) antigen expression in the human hepatoma cell line PLC/PRF/5. Ribavirin, amantadine, glycyrrhizin, and pyrazofurin were selected in this screening test and were studied further. The selectivity indi