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Studies on isocyanides. Synthesis ofN-substituted 2-isocyanocarboxamides

✍ Scribed by Bossio, Ricardo ;Marcaccini, Stefano ;Pepino, Roberto

Book ID
102366161
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
209 KB
Volume
1990
Category
Article
ISSN
0947-3440

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✦ Synopsis

Abstract

The Ugi four‐component condensation between isocyanides, aldehydes, and ammonium formate affords N‐substituted 2‐formylaminocarboxamides 1 which are dehydrated with POCl~3~/NEt~3~ to give the title compounds.

📜 SIMILAR VOLUMES

Studies on isocyanides and related compo
Studies on isocyanides and related compounds. – Synthesis and cyclization ofN-substituted 1-isocyano-1-cycloalkanecarboxamides
✍ Bossio, Ricardo ;Marcaccini, Stefano ;Paoli, Paola ;Papaleo, Sandro ;Pepino, Rob 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 481 KB

## Abstract The Ugi four‐component condensation between cycloalkanones, isocyanides, and ammonium formate affords __N__‐substituted 1‐formylamino‐1‐cycloalkanecarboxamides 1 which are dehydrated to give the corresponding isocyanides 2. Compounds 2 are cyclized with arylsulfenyl thiocyanates to 1,3‐