Studies on homocysteine and dehydroepiandrosterone sulphate plasma levels in alzheimer’s disease patients and in Parkinson’s disease patients
✍ Scribed by S. Genedani; G. Rasio; P. Cortelli; F. Antonelli; D. Guidolin; M. Galantucci; K. Fuxe; L. F. Agnati
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 125 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1029-8428
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## Abstract Homocysteine (Hcy) is a risk factor for vascular diseases, cognitive impairment, and dementia. Elevated plasma concentrations of Hcy have been found recently in Parkinson's disease (PD) patients treated with levodopa, suggesting that levodopa is a cause of hyperhomocysteinemia (HHcy). T
## Abstract Levodopa (L‐dopa) administered with a dopadecarboxylase inhibitor (DDI) increases homocysteine plasma levels. This may support the onset of atherosclerosis‐related disorders and neuropsychiatric complications in patients with Parkinson's disease (PD). This homocysteine elevation is cons