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Studies on Heterocyclic Enaminonitriles, XIII. Reactions of EthylN-2-(3-Cyano-4,5-dihydro-2-furyl)carbamates with Sodium Iodide

✍ Scribed by Maruoka, Hiroshi ;Yamagata, Kenji ;Yamazaki, Motoyoshi

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
338 KB
Volume
1993
Category
Article
ISSN
0947-3440

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✦ Synopsis

Abstract

The reaction of ethyl N‐2‐(3‐cyano‐4,5‐dihydro‐2‐furyl)carbamate (1), 1‐cyano‐N‐(ethoxycarbonyl)cyclopropanecarboxamide (2), and ethyl 3‐cyano‐2‐oxo‐1‐pyrrolidinecarboxylate (3) with sodium iodide gave 3‐ethyl‐2‐oxo‐3‐pyrrolidinecarbonitrile (5). Similarly, the reaction of ethyl N‐2‐[3‐cyano‐4,5‐dihydro‐4‐(or ‐5‐)phenyl‐2‐furyl]carbamate (7 or 8) and trans‐1‐cyano‐N‐(ethoxycarbonyl)‐2‐phenylcyclopropane‐carboxamide (9) afforded 3‐ethyl‐2‐oxo‐5‐phenyl‐3‐pyrrolidinecarbonitrile (10).

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