𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Studies on Heterocyclic Enaminonitriles, XII. Reactions of 4,5-Dihydro-2-morpholino- (and -2-pyrrolidino)-3-furancarbonitriles with Dichlorocarbene

✍ Scribed by Yamagata, Kenji ;Takaki, Mikiko ;Yamazaki, Motoyoshi

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
415 KB
Volume
1992
Category
Article
ISSN
0947-3440

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The reaction of 4,5‐dihydro‐2‐morpholino‐ (and ‐2‐pyrrolidino)‐3‐furancarbonitriles 1a, c, d and 2a, c, d with dichlorocarbene gave 4‐(2,4‐pentadienoyl)morpholines 3a, c, d and 1‐(2,4‐pentadienoyl)pyrrolidines 4a, c, d. Similarly, the reaction of 4,5‐dihydro‐5‐methyl‐2‐morpholino‐ (and ‐2‐pyrrolidino)‐3‐furancarbonitrile 1b and 2b afforded the corresponding 4‐(2‐chloro‐3‐cyano‐2,4‐hexadienoyl)morpholine (3b) and 1‐(2‐chloro‐3‐cyano‐2,4‐hexadienoyl)pyrrolidine (4b). The starting compounds 1a–d and 2a–d were synthesized by the reaction of 2‐amino‐4,5‐dihydro‐3‐furancarbonitriles with morpholine (and pyrrolidine) in the presence of trimethylamine hydrochloride in dioxane.

📜 SIMILAR VOLUMES

Studies on Heterocyclic Enaminonitriles,
Studies on Heterocyclic Enaminonitriles, XVI. Reactions of 2-Benzamido-4,5-dihydro-3-thiophene- and -3-furancarbonitriles with Cyanomethylene Compounds
✍ Yamagata, Kenji ;Hashimoto, Yoshichika ;Yamazaki, Motoyoshi 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB

## Abstract The reactions of 2‐benzamido‐4,5‐dihydro‐3‐thiophene‐ and ‐3‐furancarbonitriles (1 and 2) with ethyl or methyl cyanoacetate and malononitrile (2 equiv.) in the presence of sodium hydride (1 equiv.) in dimethyl sulfoxide at 140°C gave ethyl or methyl cyano[3‐cyano‐4,5‐dihydro‐2(3__H__)‐t

Studies on Heterocyclic Enaminonitriles,
Studies on Heterocyclic Enaminonitriles, XIII. Reactions of EthylN-2-(3-Cyano-4,5-dihydro-2-furyl)carbamates with Sodium Iodide
✍ Maruoka, Hiroshi ;Yamagata, Kenji ;Yamazaki, Motoyoshi 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 338 KB

## Abstract The reaction of ethyl __N__‐2‐(3‐cyano‐4,5‐dihydro‐2‐furyl)carbamate (1), 1‐cyano‐__N__‐(ethoxycarbonyl)cyclopropanecarboxamide (2), and ethyl 3‐cyano‐2‐oxo‐1‐pyrrolidinecarboxylate (3) with sodium iodide gave 3‐ethyl‐2‐oxo‐3‐pyrrolidinecarbonitrile (5). Similarly, the reaction of ethyl

ChemInform Abstract: Synthesis of 1,3-Ox
ChemInform Abstract: Synthesis of 1,3-Oxazines and Furo[2,3-b]pyrans by Reaction of 2-Amino-4,5-dihydro-3-furancarbonitriles with Dibenzoyldiazomethanes.
✍ K. YAMAGATA; K. AKIZUKI; M. YAMAZAKI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Five-Membered 2,3-Dioxo Heterocycles. Pa
Five-Membered 2,3-Dioxo Heterocycles. Part 51. Reaction of 3-Aroyl-2,4-dihydro-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones with 3-Amino-5,5-dimethylcyclohex-2-en-1-one.
✍ N. L. Racheva; S. N. Shurov; Z. G. Aliev; A. N. Maslivets 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 21 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.