✦ LIBER ✦

Studies on flexibility and binding affinity of Asp25 of HIV-1 protease mutants

✍ Scribed by Rituraj Purohit; R. Rajasekaran; C. Sudandiradoss; C. George Priya Doss; K. Ramanathan; Sethumadhavan Rao

Book ID: 116541999
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 470 KB
Volume: 42
Category: Article
ISSN: 0141-8130
DOI: 10.1016/j.ijbiomac.2008.01.011

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Purification of HIV-1 wild-type protease

Purification of HIV-1 wild-type protease and characterization of proteolytically inactive HIV-1 protease mutants by pepstatin A affinity chromatography

✍ Ewald M. Wondrak; John M. Louis; Peter T. Mora; Stephen Oroszlan 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 625 KB

Flexibility of Monomeric and Dimeric HIV

Flexibility of Monomeric and Dimeric HIV-1 Protease †

✍ Levy, Yaakov; Caflisch, Amedeo 📂 Article 📅 2003 🏛 American Chemical Society 🌐 English ⚖ 888 KB

Conformational flexibility of the cataly

Conformational flexibility of the catalytic Asp dyad in HIV-1 protease: An ab initio study on the free enzyme

✍ Stefano Piana; Paolo Carloni 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB 👁 2 views

The enzyme protease from the human immunodeficiency virus type 1 (HIV-1 PR) is one of the main targets for therapeutic intervention in AIDS. Computer modeling is useful for probing the binding of novel ligands, yet empirical force fieldbased methods have encountered problems in adequately describing

Stereoisomers of Cyclic Urea HIV-1 Prote

Stereoisomers of Cyclic Urea HIV-1 Protease Inhibitors: Synthesis and Binding Affinities

✍ Kaltenbach, Robert F.; Nugiel, David A.; Lam, Patrick Y. S.; Klabe, Ronald M.; S 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 161 KB

HIV-1 Protease Inhibitors: Enthalpic ver

HIV-1 Protease Inhibitors: Enthalpic versus Entropic Optimization of the Binding Affinity †

✍ Velazquez-Campoy, Adrian; Todd, Matthew J.; Freire, Ernesto 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 299 KB

Prediction of HIV-1 Protease/Inhibitor A

Prediction of HIV-1 Protease/Inhibitor Affinity using RosettaLigand

✍ Gordon Lemmon; Kristian Kaufmann; Jens Meiler 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 894 KB