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Studies on cyclohexane derivatives: III. A chemical proof of the configurations of the two 1-isopropyl-4-methylcyclohexanes (para-menthanes)

✍ Scribed by H. van Bekkum; D. Medema; P. E. Verkade; B. M. Wepster

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
380 KB
Volume
81
Category
Article
ISSN
0165-0513

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✦ Synopsis

Abstract

The configurations of the two 1‐isopropyl‐4‐methylcyclohexanes (para‐menthanes) were determined by means of syntheses starting from pure cis‐and pure trans‐4‐methylcyclohexanecarboxylic acid.

📜 SIMILAR VOLUMES

Studies on cyclohexane derivatives: I. A
Studies on cyclohexane derivatives: I. A chemical proof of the configuration of the two 1,4-dimethyl-cyclohexanes
✍ H. van Bekkum; A. A. B. Kleis; A. A. Massier; P. E. Verkade; B. M. Wepster 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 415 KB

## Abstract Starting from __cis__‐ and __trans__‐cyclohexane‐1,4‐dicarboxylic acid, __cis__‐and __trans__‐1,4‐dimethylcyclohexane are prepared in a way that leaves no doubt as to the configuration of the latter compounds.

Studies on cyclohexane derivatives: IV P
Studies on cyclohexane derivatives: IV Preparation and chemical proof of the configurations of the two 4-isopropylcyclohexanecarboxylic acids
✍ H. van Bekkum; A. A. B. Kleis; D. Medema; P. E. Verkade; B. M. Wepster 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 487 KB

## Abstract The preparation of pure low‐melting 4‐isopropylcyclohexanecarboxylic acid (m.p. 40–41°) is described for the first time. It was isolated from mixtures of the low‐melting and the high‐melting isomer, making use of the fact that only the latter gives an inclusion compound with thiourea.

Studies on cyclohexane derivatives: II.
Studies on cyclohexane derivatives: II. Preparation and chemical proof of the configuration of the two 4-methylcyclohexanecarboxylic acids
✍ H. van Bekkum; A. A. B. Kleis; A. A. Massier; D. Medema; P. E. Verkade; B. M. We 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 777 KB

## Abstract The preparation of pure low‐melting 4‐methylcyclohexanecarboxylic acid (m.p. 30.5‐31.5°) is described for the first time. By chemical means it is proved that low‐melting 4‐methylcyclohexanecarboxylic acid possesses the __cis__‐configuration and the high‐melting isomer the __trans__‐con