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Studies On Cyclic Nucleotide Metabolism In Tetrahymena Pyriformis: Partial Characterization of Cyclic Amp- and Cyclic Gmp-Dependent Phosphodiesterases*

โœ Scribed by KUDO, SHUZO ;NAKAZAWA, KINYA ;NOZAWA, YOSHINORI


Book ID
109247431
Publisher
Wiley (Blackwell Publishing)
Year
1980
Tongue
English
Weight
431 KB
Volume
27
Category
Article
ISSN
0022-3921

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An insulin mediator which inhibits cAMP-dependent protein kinase has been purified approximately 1000-2000-fold from skeletal muscle. Following heat treatment, charcoal adsorption and Sephadex G-25 sieving, Sephadex G-15 sieving and HPLC over an anion exchange column were performed. The mediator has