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Studies on 3,5-Diaminopyrazoles: Synthesis of New Polyfunctionally Substituted Pyrazoloazines and Pyrazoloazoles

✍ Scribed by Nadia S. Ibrahim; Kamal U. Sadek; Fatma A. Abdel-Al

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 301 KB
Volume: 320
Category: Article
ISSN: 0365-6233
DOI: 10.1002/ardp.19873200310

No coin nor oath required. For personal study only.

✦ Synopsis

New aminopyrazolo [ 1,5-a]pyrimidines, pyrazolo[ 3,4-dlpyrimidines and imidazof 1,2-blpyrazoles were synthesised from ethyl 3,5-diaminopyrazole-4-carboxylate (1).

Studien iiber 3,5-Diaminopyrazole: Synthese neuer polyfunktionell substituierter Pyrazolazine und Pyrazoloazole

Einige neue Aminopyrazolol l,S-alpyrimidine, Pyrazolo[ 3,4-dlpyrimidine und Imidazo[1,2-blpyrazole wurden aus 3,5-Diamino-4-ethoxycarbonylpyrazol(l) hergestellt.

Pyrazolo[ 1,5-alpyrimidine derivatives are important due to their ability to inhibit 3',5'-cyclic AMP phosphodiesterase and their cardiotropic properties'. 2). Moreover, antipyretic, antiinflammatory and anticancer activities have been reported for many pyrazolo[ 1,5-alpyrimidine derivative^^.^).

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