In this study, gauge repeatability and reproducibility (gauge R&R) was used to analyze variability for USP apparatus 2 dissolution measurement systems. Experiments were designed to assess the variability due to apparatus, operator, and sample tablet. Since dissolution testing is a destructive test,
Studies of variability in dissolution testing with USP apparatus 2
โ Scribed by Gao, Zongming (author);Moore, Terry W. (author);Smith, Anjanette P. (author);Doub, William H. (author);Westenberger, Benjamin J. (author)
- Publisher
- John Wiley and Sons Inc.
- Year
- 2007
- Tongue
- English
- Weight
- 273 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The authors thank Robert E. Graham for providing the degradation products and commercial samples. Laura M. Tuck lor her analytical work on the enema, and Stephen M. Walters for a constructive editorial review.
Blend time, the time to achieve a predefined level of homogeneity of a tracer in a mixing vessel, is an important parameter to evaluate the mixing efficiency of mixing devices. In this work, the blend time required to homogenize the liquid content of a USP Dissolution Testing Apparatus II under a nu
We present a detailed study of hydrodynamics inside the flow-through dissolution apparatus when operated according to USP recommendations. The pulsatile flow inside the flow-through cell was measured quantitatively using magnetic resonance imaging (MRI) at a spatial resolution of 234 ร 234 :m 2 and