Studies of folding and misfolding using simplified models
β Scribed by Nikolay V Dokholyan
- Book ID
- 113883042
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 316 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0959-440X
No coin nor oath required. For personal study only.
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This Book Provides An Overview On What Researchers Have Learned About Unfolded Peptides And How This Knowledge Facilitates The Understanding Of (a) The Folding Process, (b) The Binding Of Ligands To Receptor Molecules, And (c) Peptide Self-aggregation. In This Context, Different Experimental, Theore
## Abstract Energyβbased methods for calculating timeβaveraged peptide structures are important for rational peptide design, for defining local structure propensities in large protein chains, and for exploring the sequence determinants of amyloid formation. Highβend methods are currently too slow t