This Book Provides An Overview On What Researchers Have Learned About Unfolded Peptides And How This Knowledge Facilitates The Understanding Of (a) The Folding Process, (b) The Binding Of Ligands To Receptor Molecules, And (c) Peptide Self-aggregation. In This Context, Different Experimental, Theoretical, And Computational Concepts And Approaches Are Introduced. This Book Can Become A Very Useful Addition For Graduate-level Courses On Protein Folding For The Education Of Undergraduate And Graduate Students In Research Groups, Which Are Exploring Peptide Self-aggregation For Biomedical And Biotechnological Purposes-- Edited By Reinhard Schweitzer-stenner. Includes Bibliographical References And Index. Why Are We Interested In The Unfolded Peptides And Proteins? / Vladimir N. Uversky And A. Keith Dunker -- Exploring The Energy Landscape Of Small Peptides And Proteins By Molecular Dynamics Simulations / Gerhard Stock ... [et Al.] -- Local Backbone Preferences And Nearest-neighbor Effects In The Unfolded And Native States / Joe Debartolo ... [et Al.] -- Short-distance Fret Applied To The Polypeptide Chain / Maik H. Jacob And Werner M. Nau -- Solvation And Electrostatics As Determinants Of Local Structural Order In Unfolded Peptides And Proteins / Franc Avbelj -- Experimental And Computational Studies Of Polyproline Ii Propensity / W. Austin Elam, Travis P. Schrank, And Vincent J. Hilser -- Mapping Conformational Dynamics In Unfolded Polypeptide Chains Using Short Model Peptides By Nmr Spectroscopy / Daniel Mathieu ... [et Al.] -- Secondary Structure And Dynamics Of A Family Of Disordered Proteins / Pranesh Narayanaswami And Gary W. Daughdrill -- Binding Promiscuity Of Unfolded Peptides / Christopher J. Oldfield ... [et Al.] -- Intrinsic Flexibility Of Nucleic Acid Chaperone Proteins From Pathogenic Rna Viruses / Roland Ivanyi-nagy, Zuzanna Makowska, And Jean-luc Darlix -- Self-assembling Alanine-rich Peptides Of Biomedical And Biotechnological Relevance / Thomas J. Measey And Reinhard Schweitzer-stenner -- Structural Elements Regulating Interactions In The Early Stages Of Fibrillogenesis: A Human Calcitonin Model System / Rosa Maria Vitale ... [et Al.] -- Solution Nmr Studies Of Aฮฒ Monomers And Oligomers / Chunyu Wang -- Thermodynamic And Kinetic Models For Aggregation Of Intrinsically Disordered Proteins / Scott L. Crick And Rohit V. Pappu -- Modifiers Of Protein Aggregation--from Nonspecific To Specific Interactions / Michal Levy-sakin, Roni Scherzer-attali, And Ehud Gazit -- Computational Studies Of Folding And Assembly Of Amyloidogenic Proteins / J. Srinivasa Rao, Brigita Urbanc, And Luis Cruz.