Studies of DNA-strand breaks induced in human fibroblasts by chemical mutagens/carcinogens
✍ Scribed by M. Nordenskjöld; S. Söderhäll; P. Moldéus
- Book ID
- 113191576
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 465 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0027-5107
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In vitro exposure of normal human diploid fibroblasts (strain VH-10) to ethylene oxide (EtO) induced DNA strand breaks in the dose range of 2.5-30 mMh of EtO. Alkaline DNA unwinding (ADU), neutral filter elution (NFE), pulsed field gel electrophoresis (PFGE), and the comet assay were used to measure