Studies of bioactive heterocycles: facile thio-Claisen rearrangement of propargylthio[1]benzopyran-2-ones
โ Scribed by K.C Majumdar; S.K Ghosh
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 148 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
Several aryl-1(3-bromo-2-methyl-prop-2-ene) ethers 2 have been prep,ared an'd their thermal rearrangements in PEG-405 in the presence of N,N-diethylaniline were Found to yield the title compounds.
Thermal amino-Claisen rearrangement of 4-N-(aryloxybut-2-ynyl),N-methyl-aminocoumarins (8a-e) in refluxing odichlorobenzene gave 4-aryloxymethylene-1-methyl-1,2,3-trihydropyrido[3,2-c][1]benzopyran-5-ones (9a-e) in 56-72% isolated yields. Substrates (8a-f) were prepared from 4-chlorocoumarin (6a,b)