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Studies of benzylisoquinolines. Comparison of the reactivity of the methylene group in 1-benzyl and 4-benzylisoquinolines

✍ Scribed by Claude Vaccher; Pascal Berthelot; Monique Devergnies; Michel Debaert; Jean-Paul Bonte; Claude Viel


Book ID
112129297
Publisher
Journal of Heterocyclic Chemistry
Year
1989
Tongue
English
Weight
247 KB
Volume
26
Category
Article
ISSN
0022-152X

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πŸ“œ SIMILAR VOLUMES


A novel C–N cleavage in isoquinolines al
✍ MΓ³nica Treus; Juan C EstΓ©vez; Luis Castedo; RamΓ³n J EstΓ©vez πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 93 KB

Treatment of N-carbethoxy-1-benzylideneisoquinolines with LDA gives N-ethoxycarbonyl-1-amino-1-(2-vinylphenyl)-2-phenylethylenes, which can easily be transformed into N-carbethoxy-1-amino-2-phenylnaphthalenes. BichlerΒ±Napieralski reaction of these latter compounds aords the corresponding benzo[c]phe