Studies in phlebitis. VII: In vitro and
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Paul B. Myrdal; Pahala Simamora; Yosyong Surakitbanharn; Samuel H. Yalkowsky
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Article
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1995
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John Wiley and Sons
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English
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We describe a computational model and an in vitro experiment for assessing whether or not a pH-solubilized drug has the potential to precipitate upon dilution with blood. The computational model enables an efficient means of selecting buffer concentration and pH, and the in vitro test provides a sim