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Studies in C-terminal sequencing: New reagents for the synthesis of peptidylthiohydantoins

✍ Scribed by Narmada R. Shenoy; John E. Shively; Jerome M. Bailey


Publisher
Springer
Year
1993
Tongue
English
Weight
972 KB
Volume
12
Category
Article
ISSN
1573-4943

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A new linker for the synthesis of C-term
✍ Jean-SΓ©bastien Fruchart; HΓ©lΓ¨ne Gras-Masse; Oleg Melnyk πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 268 KB

A tartaric acid-based linker was elaborated on an amino PEGA resin for the synthesis of C-terminal cx-oxoaldehydes. A solid phase periodic oxidation allowed the formation of the glyoxylyl moiety and the separation of the final product from the solid support.