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Studies directed toward the syntheses of amphidinolides: formal total synthesis of (−)-amphidinolide P

✍ Scribed by Tushar K Chakraborty; Sanjib Das

Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 68 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)00450-6

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✦ Synopsis

A formal total synthesis of (-)-amphidinolide P (1) has been achieved via an efficient convergent strategy for the stereoselective construction of the two advanced intermediates 2 and 3, used recently by Williams et al. in their synthesis of the same molecule.

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