Structures of Zinc Ketone Enolates
β Scribed by Hlavinka, Mark L.; Hagadorn, John R.
- Book ID
- 126912709
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 126 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0276-7333
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π SIMILAR VOLUMES
## Abstract An Ξ±βalkylation of the 2βmethylcycloalkanones 1 and 4 at the higher substituted carbon can be achieved by thioalkylation of the corresponding zinc enolates with the Ξ±βchlorosulfides 3. The desulfurization can be carried out with either Raney nickel or lithium in diethylamine for compoun
Kinetic cyanations of ketone enolates using p-toluenesulfonyl cyanide provide efficient routes to B-ketonitriles. During the course of a natural product synthesis study going on in our laboratory we required a means of effecting the ketone cyanation illustrated in equation 1. Examination of existing