The title compound, C~25~H~27~N~3~, possesses an essentially planar, fused tricyclic platform, from which two __p__-tolyl rings project on the same face to create a hydrophobic pocket.
✦ LIBER ✦
Structures of 1,2,3,4-tetrahydro-6H-pyrimido[2,1-b]-quinazolin-6-one and its hydrochloride
✍ Scribed by Marek L. Glówka; Andrzej Olczak; Lucyna Korzycka
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 277 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1572-8854
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## Abstract The reaction of 1‐aryl‐3‐(dimethylamino)‐1‐propanones 1 with one equivalent of 4,5‐diamino‐1__H__‐pyrimidin‐6‐ones 2, in acidic medium, leads to the formation of 4‐aryl‐2,3,6,7‐tetrahydro‐1__H__‐pyrimido[4,5‐__b__]‐[1,4]diazepin‐6‐ones 3. The structure elucidation of the products is bas