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Structure–function studies on Taiwan cobra long neurotoxin homolog

✍ Scribed by Long-sen Chang; Shinne-ren Lin; Jeh-jeng Wang; Wan-Ping Hu; Bin-nan Wu; Hsien-bin Huang


Book ID
114148760
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
488 KB
Volume
1480
Category
Article
ISSN
0167-4838

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Modification of His-47 and removal of the N-terminal octapeptide caused a different effect on the structure of Naja naja atra (Taiwan cobra) phospholipase A2 (PLA2). Unlike native enzyme, Ca2+ induced an alteration in the structural flexibility of His-modified PLA2. Moreover, the spatial positions o