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Structure–activity relationships of neuropeptide FF and related peptidic and non-peptidic derivatives

✍ Scribed by Neha Vyas; Catherine Mollereau; Gwénaël Chevé; Christopher R. McCurdy

Book ID
116830927
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
192 KB
Volume
27
Category
Article
ISSN
0196-9781

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Peptide deformylase (PDF), which removes the formyl group at the N-terminal methionine residue of nascent protein, has been recognized as a potent target for antibacterial therapy. We report herein the synthesis and structure-activity relationship studies of non-peptide PDF inhibitors.