Structure–Activity Relationship Study of 16 a-Thiocamptothecins: an Integrated In Vitro and In Silico Approach
✍ Scribed by Dr. Cristian Samorì; Dr. Giovanni L. Beretta; Dr. Greta Varchi; Dr. Andrea Guerrini; Dr. Simone Di%emsp14;Micco; Dr. Serena Basili; Prof. Giuseppe Bifulco; Prof. Raffaele Riccio; Prof. Stefano Moro; Dr. Ezio Bombardelli; Dr. Franco Zunino; Dr. Gabriele Fontana
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 507 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1860-7179
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The expiratory bradypnea indicative of upper airway irritation in mice was evaluated during a 15-min oronasal exposure to increasing concentrations of sixteen aliphatic amines. The airborne concentration resulting in a 50% decrease in the respiratory rate of mice ( R D ~~) was calculated for each te