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Synthesis, in vitro/in vivo Antifungal Evaluation and Structure—Activity Relationship Study of 3(2H)-Pyridazinones.

✍ Scribed by Ricardo D. Enriz; et al. et al.

Publisher: John Wiley and Sons
Year: 2004
Weight: 76 KB
Volume: 35
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200408142

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## Abstract As part of our ongoing research effort to develop new antimitotic agents based on the recently reported pyrimido[4,5‐__c__]quinoline‐1(2__H__)‐one ring skeleton, we were interested in identifying structural elements that contribute to the cytotoxicity of this class of compounds. The eff