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Structure−Activity Relationship Studies on the 5-HT 1A Receptor Affinity of 1-Phenyl-4-[ω-(α- or β-tetralinyl)alkyl]piperazines. 4 1

✍ Scribed by Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola A.; Leopoldo, Marcello; Tortorella, Vincenzo; Fornaretto, Maria Gioia; Caccia, Carla; McArthur, Robert A.


Book ID
126981574
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
405 KB
Volume
39
Category
Article
ISSN
0022-2623

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ChemInform Abstract: 1-[ω-(4-Arylpiperaz
✍ M. L. LOPEZ-RODRIGUEZ; M. J. MORCILLO; T. K. ROVAT; E. FERNANDEZ; A. M. SANZ; L. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 40 KB 👁 1 views

## 1-[ω-(4-Arylpiperazin-1-yl)alkyl] -3-diphenylmethylene-2,5pyrrolidinediones as 5-HT 1A Receptor Ligands: Study of the Steric Requirements of the Terminal Amide Fragment on 5-HT 1A Affinity/Selectivity. -Two different methods are used to prepare the desired title compounds (IV) and (VII) which