H T I A receptor ligands, 1 -(2-methoxyphenyl)piperazines, hydrophobic effects, ~-H T I A receptor agonists, LLR induction
✦ LIBER ✦
Structure−Activity Relationship Studies on the 5-HT 1A Receptor Affinity of 1-Phenyl-4-[ω-(α- or β-tetralinyl)alkyl]piperazines. 4 1
✍ Scribed by Perrone, Roberto; Berardi, Francesco; Colabufo, Nicola A.; Leopoldo, Marcello; Tortorella, Vincenzo; Fornaretto, Maria Gioia; Caccia, Carla; McArthur, Robert A.
- Book ID
- 126981574
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 405 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0022-2623
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## 1-[ω-(4-Arylpiperazin-1-yl)alkyl] -3-diphenylmethylene-2,5pyrrolidinediones as 5-HT 1A Receptor Ligands: Study of the Steric Requirements of the Terminal Amide Fragment on 5-HT 1A Affinity/Selectivity. -Two different methods are used to prepare the desired title compounds (IV) and (VII) which