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Structure–activity relationship of phenytoinergic antiepileptic drugs related to ameltolide

✍ Scribed by Ashok E. Philip; Jacques H. Poupaert; Gwénaël Chevé; Giulio Muccioli; Didier Lambert; Christopher R. McCurdy


Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
198 KB
Volume
16
Category
Article
ISSN
1054-2523

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Several tetrapeptide analogs of dermorphin have been studied by means of 'H-nmr spectroscopy at 500 MHz in DMSO-d,. In spite of the unfavorable properties of the solvent, it is possible to extract key structural information that, combined with the biological activity of the peptides, yields a struct