𝔖 Bobbio Scriptorium
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Structure Reassignment of Laurefurenynes A and B by Computation and Total Synthesis

✍ Scribed by Shepherd, David J.; Broadwith, Phillip A.; Dyson, Bryony S.; Paton, Robert S.; Burton, Jonathan W.


Book ID
120924501
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
472 KB
Volume
19
Category
Article
ISSN
0947-6539

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## Abstract The first total synthesis of tasiamide B, an octapeptide bearing 4‐amino‐3‐hydroxy‐5‐phenylpentanoic acid unit isolated from the marine cyanobacteria __Symploca__ sp. is described. A simple and efficient way was found to avoid the pyroglutamylation of __N__^Ξ±^‐Me‐Gln and led to a reassi