Structure, organization and expression of the eukaryotic translation initiation factor 5, eIF-5, gene in Zea mays
✍ Scribed by Ignacio López Ribera; Pere Puigdomènech
- Book ID
- 117523887
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 178 KB
- Volume
- 240
- Category
- Article
- ISSN
- 0378-1119
No coin nor oath required. For personal study only.
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## Abstract A gene coding for a protein homologous to a translation initiation factor of eukaryotes, eIF5A, was cloned from __Methanococcus jannaschii__, a hyperthermophile with an optimum growth temperature of 85 °C. The protein was overexpressed, purified and crystallized. The crystals were obtai
## Abstract Eukaryotic translation initiation factor 5A (eIF5A) has a unique character: the presence of an unusual amino acid, hypusine, which is formed by post‐translational modifications. Even before the identification of hypusination in eIF5A, the correlation between hypusine formation and prote