Insights on eukaryotic translation initiation factor 5A (eIF5A) in the brain and aging
β Scribed by Augusto D. Luchessi; Tavane D. Cambiaghi; Adilson S. Alves; Lucas T. Parreiras-E-Silva; Luiz R.G. Britto; Claudio M. Costa-Neto; Rui Curi
- Book ID
- 113503623
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 721 KB
- Volume
- 1228
- Category
- Article
- ISSN
- 0006-8993
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## Abstract Using comparative proteomic and genomic approaches, the authors identified eukaryotic translation initiation factor 5A (eIF5A) as an oncofetal molecule highly abundant in mouse embryonic livers and human hepatocellular carcinoma (HCC) cell lines. To evaluate the oncogenic role and progn