Structure of the Tfb1/p53 Complex: Insights into the Interaction between the p62/Tfb1 Subunit of TFIIH and the Activation Domain of p53
β Scribed by Paola Di Lello; Lisa M. Miller Jenkins; Tamara N. Jones; Bao D. Nguyen; Toshiaki Hara; Hiroshi Yamaguchi; Jimmy D. Dikeakos; Ettore Appella; Pascale Legault; James G. Omichinski
- Book ID
- 116754221
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 415 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1097-2765
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Recent experimental data reveal that the peptide fragment of Azurin called p28, constituted by the amino acid residues from 50 to 77 of the whole protein, retains both the Azurin cellular penetration ability and antiproliferative activity. p28 is hypothesized to act by stabilizing the wellβknown tum
## Abstract It is known that the half life of the tumor suppressor p53 can be increased by the interaction with the bacterial protein azurin, resulting in an enhanced antiβtumoral activity. The understanding of the molecular mechanisms on the basis of this phenomenon can open the way to new antiβca