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Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

✍ Scribed by Laue, Ernest D.; Mott, Helen R.; Owen, Darerca; Nietlispach, Daniel; Lowe, Peter N.; Manser, Edward; Lim, Louis


Book ID
109645019
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
483 KB
Volume
399
Category
Article
ISSN
0028-0836

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## Abstract Structural formation of segments plays pivotal roles in protein folding and stability, but how the segment influences the structural ensemble remains elusive. We engineered two hybrid proteins by replacing the central helical segment of immunoglobulin G binding domain of streptococcal p