Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’ protein
✍ Scribed by Rosen, Michael K.; Abdul-Manan, Norzehan; Aghazadeh, Behzad; Liu, Grace A.; Majumdar, Ananya; Ouerfelli, Ouathek; Siminovitch, Katherine A.
- Book ID
- 109644961
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 482 KB
- Volume
- 399
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/20726
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Wiskott-Aldrich syndrome is an X-linked disorder characterized by thrombocytopenia, eczema and immunodeficiency. The Wiskott-Aldrich syndrome protein and the gene that encodes it have been identified by positional cloning and the protein has been shown to contain a pleckstrin-homology domain, a GTPa
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