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Structure of the PTEN Tumor Suppressor Associated with the Fluid Lipid Membranes

โœ Scribed by Shenoy, Siddharth; Shekhar, Prabhanshu; Nanda, Hirsh; Heinrich, Frank; Ross, Alonzo H.; Loesche, Mathias


Book ID
122193647
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
60 KB
Volume
100
Category
Article
ISSN
0006-3495

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## Background: Germ-line and sporadic mutations in the tumor suppressor gene pten (also known as mmac or tep1), which encodes a dual-specificity phosphatase, cause a variety of cancers such as cowden disease, glioblastoma, endometrial carcinoma and prostatic cancer. pten is widely expressed, and co