𝔖 Bobbio Scriptorium
✦   LIBER   ✦

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

✍ Scribed by Akira Suzuki; José Luis de la Pompa; Vuk Stambolic; Andrew J. Elia; Takehiko Sasaki; Ivén del Barco Barrantes; Alexandra Ho; Andrew Wakeham; Annick ltie; Wilson Khoo; Manabu Fukumoto; Tak W. Mak

Book ID
114320520
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
207 KB
Volume
8
Category
Article
ISSN
0960-9822

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

High cancer susceptibility and embryonic
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
✍ Akira Suzuki; José Luis de la Pompa; Vuk Stambolic; Andrew J. Elia; Takehiko Sas 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 207 KB

## Background: Germ-line and sporadic mutations in the tumor suppressor gene pten (also known as mmac or tep1), which encodes a dual-specificity phosphatase, cause a variety of cancers such as cowden disease, glioblastoma, endometrial carcinoma and prostatic cancer. pten is widely expressed, and co

Association of aberrant methylation of t
Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer
✍ Shuiying Hu; Dingxie Liu; Ralph P. Tufano; Kathryn A. Carson; Eli Rosenbaum; Yor 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 208 KB 👁 1 views

## Abstract The role of aberrant tumor suppressor gene methylation in the aggressiveness of papillary thyroid cancer (PTC) has not been documented. By showing promoter methylation‐induced gene silencing in PTC‐derived cell lines, we first demonstrated the functional consequence of methylation of se