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Expression of SCUBE2 gene declines in high grade endometrial cancer and associates with expression of steroid hormone receptors and tumor suppressor PTEN

✍ Scribed by Skrzypczak, Maciej; Lattrich, Claus; Häring, Julia; Schüler, Susanne; Ortmann, Olaf; Treeck, Oliver

Book ID
127057349
Publisher
Informa plc
Year
2013
Tongue
English
Weight
286 KB
Volume
29
Category
Article
ISSN
0951-3590

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## Background: Germ-line and sporadic mutations in the tumor suppressor gene pten (also known as mmac or tep1), which encodes a dual-specificity phosphatase, cause a variety of cancers such as cowden disease, glioblastoma, endometrial carcinoma and prostatic cancer. pten is widely expressed, and co