Structure of the product complex of acetyl-Ala-Pro-Ala with porcine pancreatic elastase at 1.65 Å resolution
✍ Scribed by E.F. Meyer Jr; R. Radhakrishnan; G.M. Cole; L.G. Presta
- Book ID
- 118918668
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 755 KB
- Volume
- 189
- Category
- Article
- ISSN
- 0022-2836
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## Abstract The peptide trifluoroacetyl‐Leu‐Ala‐(__p__‐trifluoromethylanilide), is a reversible inhibitor of pancreatic porcine elastase and is characterized by a __K__~m~ of 2.5 × 10^−8^ M. Co‐crystals of the 1:1 complex were obtained in an acetate buffer + dimethylformamide solution at pH 5.7. Di