Structure of the periodontium in cathepsin C-deficient mice
β Scribed by Susanne F. De Haar; Wikky Tigchelaar-Gutter; Vincent Everts; Wouter Beertsen
- Book ID
- 111256719
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 387 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0909-8836
No coin nor oath required. For personal study only.
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## Abstract Cathepsin B (CTSB) and cathepsin L (CTSL) are two widely expressed cysteine proteases thought to predominantly reside within lysosomes. Functional analysis of CTSL in humans is complicated by the existence of two CTSL-like homologs (CTSL and CTSL2), in contrast to mice, which possess on
## Abstract Cathepsin S (CS) is a lysosomal/endosomal cysteine protease especially expressed in cells of a mononuclear lineage including microglia. To better understand the role of CS in microglia, we investigated microglial responses after a facial nerve axotomy in CSβdeficient (CSβ/β) and wildβty