𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice

✍ Scribed by Sevenich, Lisa; Pennacchio, Len A.; Peters, Christoph; Reinheckel, Thomas

Book ID
120405991
Publisher
Walter de Gruyter GmbH & Co. KG
Year
2006
Tongue
English
Weight
353 KB
Volume
387
Category
Article
ISSN
1431-6730

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Human cathepsin L rescues the neurodegen
Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice
✍ Sevenich, Lisa; Pennacchio, Len A.; Peters, Christoph; Reinheckel, Thomas πŸ“‚ Article πŸ“… 2006 πŸ› Walter de Gruyter GmbH & Co. KG 🌐 English βš– 353 KB

## Abstract Cathepsin B (CTSB) and cathepsin L (CTSL) are two widely expressed cysteine proteases thought to predominantly reside within lysosomes. Functional analysis of CTSL in humans is complicated by the existence of two CTSL-like homologs (CTSL and CTSL2), in contrast to mice, which possess on