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Axonal degeneration in mice doubly deficient in cathepsin D or B and L

โœ Scribed by Masato Koike; Yasuo Uchiyama

Book ID
116777889
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
68 KB
Volume
68
Category
Article
ISSN
0168-0102

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## Abstract Cathepsin B (CTSB) and cathepsin L (CTSL) are two widely expressed cysteine proteases thought to predominantly reside within lysosomes. Functional analysis of CTSL in humans is complicated by the existence of two CTSL-like homologs (CTSL and CTSL2), in contrast to mice, which possess on