Structure of the cyclic sulphite and sulphate from 2,2-dimethylpropane-1,3-diol
✍ Scribed by R.S. Edmundson
- Publisher
- Elsevier Science
- Year
- 1965
- Tongue
- French
- Weight
- 148 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0040-4039
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## Abstract 2‐Oxo‐1,3,2‐dioxathiepanes and 3‐oxo‐2,4,3‐dioxathiepins, including two series of three diastereoisomers, were synthesized, isolated by HPLC and characterized by ^1^H and ^13^C NMR spectroscopy. Their conformational behaviour was studied using a computer‐assisted LIS technique and, for
## Abstract In THF solution, NaBH~4~ in the presence of (__S__)‐(‐)‐1‐(2‐chlorophenyl)‐2,2‐dimethylpropane‐1,3‐diol together with 2‐chlorobenzoic acid reduced propiophenone to 1‐ phenylpropan‐1‐ol in up to 40% enantiomeric excess (__ee__). Only 21% __ee__ was obtained without an added acid. (__R__)