Structure of the aglycone of the glycopeptide antibiotic ristomycin A
β Scribed by A. B. Silaev; B. Diarra; Zh. P. Trifonova; G. S. Katrukha
- Book ID
- 112372935
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 191 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0009-3130
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## Abstract The crystal structure of a glycopeptide antibiotic Aβ40926 aglycone was investigated by Xβray analysis at β120Β°. Aβ40926 crystallises in the orthorhombic space group __P__2~1~2~1~2~1~ with two monomers in the asymmetric unit, __a__ = 21.774(4), __b__ = 28.603(7), __c__ = 29.757(4) Γ . βC
Ikeda, Suzuki and Djerassi' extended previous joint work 2,3 on nystatin, the chemotherapeutically-important antifungal agent4 from Streptomyces noursei', and proposed constitution (I; R = OH) for nystatinolide, its hypothetical aglycone. This structure (I; R = OH) corresponds to C41H64015' and with