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Structure of N-[(3RS,5SR)-1-benzyl-5-methyl-3-pyrrolidinyl]-5-chloro-2-methoxy-4-methylaminobenzamide hydrochloride

✍ Scribed by Furuya, T. ;Fujita, S. ;Iwanami, S. ;Takenaka, A. ;Sasada, Y.

Book ID
114503511
Publisher
International Union of Crystallography
Year
1986
Tongue
English
Weight
311 KB
Volume
42
Category
Article
ISSN
0108-2701

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Synthesis of [carbonyl-14C]- and (methoxy-d3)-labeled N-[(2RS, 3RS)-1-benzyl-2-methyl-3-pyrrolidinyl] βˆ’5-chloro-2-methoxy-4-(methylamino) benzamide (YM-09151-2). A new potent neuroleptic agent
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## Abstract A new potent neuroleptic agent YM‐09151‐2, N‐[(2RS, 3RS)‐1‐benzyl‐2‐methyl‐3‐pyrrolidinyl]‐5‐chloro‐2‐methoxy‐4‐ (methylamino) benzamide (**10c**), was labeled with carbon‐14 and deuterium for biochemical studies such as metabolism and 14 pharmacokinetics. The synthesis of [carbonyl‐^14