Structure of methyl 2-(nitrooxy)ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
β Scribed by Ogawa, T. ;Matsumoto, K. ;Yokoo, C. ;Hatayama, K. ;Kitamura, K.
- Book ID
- 114509961
- Publisher
- International Union of Crystallography
- Year
- 1993
- Tongue
- English
- Weight
- 445 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0108-2701
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π SIMILAR VOLUMES
The title compound, C 26 H 23 N 3 O 8 , is a nefidipine analogue. The dihydropyridine ring has a flattened boat conformation. No hydrogen bonds exist in the crystal packing.
In the title compound, C 19 H 20 N 2 O 7 , the C atom in the 4position of the dihydropyridine ring is displaced out of the plane by 0.0461 (2) A Λ. The dihydropyridine ring plane is almost perpendicular to the benzene ring, with a dihedral angle of 88.9 (3) .
The carbon-I4 labelled compound ( 5 ) of 2-[4-(diphenylmethy1)-l -piperazinyl]ethyl methyl (?)-I ,$-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate dihydrochloride (CV-4093 (2HCI)) was synthesized for the study of its metabolism and distribution in test animals. Starting from the co